Fluticasone Propionate Science
Otri Allergy Nasal Spray the efficacy of prescription fluticasone propionate, with OTC benefits
For patients whose allergies were well controlled on a prescription intranasal corticosteroid spray (INCS) and need OTC convenience, Otri Allergy the same efficacy it delivered as a prescription medicine, with the benefits of a branded OTC medicine.1
For moderate-to-severe allergy sufferers, Otri Allergy works to block more* of the allergic cascade than single-ingredient oral antihistamines 2-5
For moderate-to-severe allergy sufferers Otri Allergy works to block more* of the allergic cascade than single-ingredient oral antihistamines:2-5
Same prescription strength, 24‐hour relief1
- The #1 prescribed intranasal corticosteroid spray (INS) ingredient* for allergic rhinitis is available OTC, and delivers the same trusted, prescription‐strength relief6-19
- First-line INS efficacy used by clinicians for over 20 years20
- 24-hour, non-drowsy relief of both nasal and ocular symptoms1
- Incidence of adverse events similar to placebo6,19
- Monotherapy with Otri Allergy may be all the allergy relief your patients need21
Relieves the symptoms of seasonal and perennial allergic rhinitis1
- In addition to treating nasal congestion, runny noses, sneezing, and itchy noses, Otri Allergy is the first OTC INS indicated to relieve itchy, watery eyes6-18
Recommended first‐line, long‐term19
- INSs such as Otri Allergy are recommended for initial and maintenance treatment of nasal allergies†,7,19
- First‐line nasal allergy treatment: Allergic Rhinitis and its Impact on Asthma (ARIA) treatment guidelines, issued in partnership with the World Health Organization, recommend INS treatments like Otri Allergy as first‐line treatment for allergic rhinitis, calling them “the most effective drugs”2,7,19
- Long‐term nasal allergy treatment: INS treatments are recognised as the most effective, long‐term treatment option for allergic rhinitis†2,,7,19
*Mechanism vs most OTC allergy pills. Otri Allergy acts on multiple inflammatory substances (histamine, prostaglandins, cytokines, tryptases, chemokines, and leukotrienes). The exact number and precise mechanism are unknown.2-5
† The Joint Task Force on Practice Parameters (the American Academy of Allergy Asthma & Immunology; the American College of Allergy, Asthma, and Immunology; and the Joint Council of Allergy, Asthma and Immunology).
Fluticasone is in the class of first line treatments for allergic rhinitis2,7,19
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Nasal Efficacy: Sustained relief of nasal symptoms in 2 studies of Otri Allergy vs placebo8,9
![Study of Otrivin Allergy All-in-One vs placebo8]()
Efficacy in seasonal allergic rhinitis (SAR)
In patients with seasonal allergic rhinitis, there was a 2x reduction at Day 4.8,#,≠
# Once‐daily 200 mcg Otri Allergy vs placebo (P<0.05).
≠ See study designs A and B.
![Perennial allergic rhinitis reduction study]()
Efficacy in perennial allergic rhinitis (PAR)
In patients with perennial allergic rhinitis, 59% had moderate or significant reduction after 24 weeks.9,#,‡
# Once‐daily 200 mcg Otri Allergy vs placebo (P<0.05).
‡ Once‐daily 200 mcg Otri Allergy vs placebo (P<0.001). Clinician‐rated total nasal scores for obstruction, rhinorrhea, sneezing, and itching.
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Ocular Efficacy: Significant relief of ocularsymptoms in a 14‐day study of Otri Allergy All-in-One vs placebo17
![ig-otrivin-global-40%-improvement-symptoms-graph750]()
Significant relief of ocular symptoms in a 14-day study of Otri Allergy vs placebo
- Clinicians reported: Significant relief of total ocular symptom scores (TOSS) [>40% improvement in TOSS from baseline at day 7 vs placebo] (P<0.001)§
- Patientsreported:Significant relief of ocular symptoms at weeks 1 and 2 (P<0.001)17
§ Based on a recalculation of the published data (see study design A).
![Oculat symptom scores graph]()
Proven to relieve itchy, watery eyes17
Clinicians reported:Significant relief of total ocular symptom scores (P<0.001):
- Mean change from baseline (%) at 7 days:Otri Allergy 200μg QD (n=821): 41.4%§Placebo (n=822): 26.4%§
- Mean change from baseline (%) at 14 days:Otri Allergy 200μg QD (n=821): 50%§Placebo (n=822): 31.3%§
At both days 7 and 14 of the study, Otri Allergy provided significant relief of itching and tearing.17
§ Based on a recalculation of the published data (see study design A).
Otri Allergy – The #1 prescribed INS ingredient for allergic rhinitis
Otri Allergy Nasal Spray
Explore Otri Allergy Nasal Spray.
Otri Allergy : prescription fluticasone propionate with OTC benefits
The Otri Nasal spray
Find out how the Otri Allergy formulation can help your patients.
